Formulation and Optimization of Metoprolol Succinate SR Matrix Tablet
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Matrix technologies have often proven popular among the oral controlled drug delivery technologies because of their simplicity, ease in manufacturing, high level of reproducibility, and stability of the raw materials.
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Produkto Aprašymas
- The purpose of controlled release systems (CRS) is to maintain drug concentration in the blood or in target tissues at a desired value as long as possible. In other words, they are able to exert a control on the drug release rate and duration. Matrix technologies have often proven popular among the oral controlled drug delivery technologies because of their simplicity, ease in manufacturing, high level of reproducibility, stability of the raw materials and dosage form, and ease of scale-up and process validation. Developing oral controlled release tablets for water soluble drugs with constant release rate has always been a challenge to the pharmaceutical technologist. Most of these water soluble drugs if not formulated properly, may readily release the drug at a faster rate and produce a toxic concentration of drug on oral administration. Hence it is a challenging task to formulate a suitable tablet dosage form for prolonged delivery of highly water soluble drugs.
| Publisher | LAP LAMBERT Academic Publishing |
| Publication date | 31 May 2022 |
| Language | English |
| Print length | 96 pages |
| ISBN-10 | 6204956108 |
| ISBN-13 | 978-6204956107 |
| Item weight | 140 g |
| Dimensions | 15.01 x 0.56 x 22 cm |
Who Should Buy?
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Hypertensive Patients
Ideal for individuals managing high blood pressure requiring consistent release of medication throughout the day.
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Heart Disease Patients
Beneficial for those with heart conditions needing long-term, stable medication to improve cardiovascular health.
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Chronic Condition Management
Suitable for patients with chronic conditions where sustained release of metoprolol ensures effective symptom control.
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Acute Blood Pressure
Not suitable for patients needing immediate blood pressure control, as it provides a gradual release of medication.
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Redakcinė apžvalga
Formulation And Optimization Of Metoprolol Succinate SR Matrix Tablet is a comprehensive guide published by LAP LAMBERT Academic Publishing on 31 May 2022. This book, written in English, spans 96 pages and delves into the detailed formulation processes and optimization strategies for metoprolol succinate sustained-release matrix tablets. It provides valuable information for researchers and professionals in the pharmaceutical industry, including systematic approaches to drug formulation. The publication's specifications include dimensions of 15.01 x 0.56 x 22 cm and an item weight of 140 g, making it a convenient reference.
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Argumentai
- In-depth guide on drug formulation techniques
- Well-structured for industry professionals
- Comprehensive optimization strategies included
- Clear and concise scientific explanations
- Suitable for both researchers and students
Minusai
- Limited illustrations may not appeal to all readers
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Savybės ir privalumai
- Controlled release systems maintain drug concentration effectively.
- Matrix technologies are simple and easy to manufacture.
- High reproducibility ensures consistent quality.
- Stable raw materials enhance overall performance.
- Designed for prolonged delivery of water-soluble drugs.
- Mitigates risk of toxic concentrations from fast drug release.
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